Zoster Vaccine and the Risk of Postherpetic Neuralgia in Patients Who Developed Herpes Zoster Despite Having Received the Zoster Vaccine
نویسندگان
چکیده
منابع مشابه
Zoster Vaccine and the Risk of Postherpetic Neuralgia in Patients Who Developed Herpes Zoster Despite Having Received the Zoster Vaccine.
BACKGROUND Although it is evident that zoster vaccination reduces postherpetic neuralgia (PHN) risk by reducing herpes zoster (HZ) occurrence, it is less clear whether the vaccine protects against PHN among patients who develop HZ despite previous vaccination. METHODS This cohort study included immunocompetent patients with HZ. The vaccinated cohort included 1155 individuals who were vaccinat...
متن کاملHerpes zoster and postherpetic neuralgia.
Herpes zoster (HZ; shingles) results from reactivation of varicella-zoster virus that has been dormant in the spinal and cranial sensory ganglia following primary infection with varicella (chickenpox), usually during childhood. In developed countries more than 95% of the adult population are seropositive for varicella-zoster virus and are therefore at risk of developing HZ. Reactivation can occ...
متن کاملHerpes zoster and postherpetic neuralgia.
Pain associated with herpes zoster arise from the virul neuritis of the suffered trigeminal or spinal dorsal ganglion. Prolonged neuritis makes an irreversible nerve injury and continuous pain impulse develops a central sensitization. A post-herpetic neuralgia is thought to be a neuropathic pain due to the irreversible nerve injury and sensitization. It is important to treat herpetic pain compl...
متن کاملVaccination against Herpes Zoster and Postherpetic Neuralgia.
BACKGROUND Herpes zoster (HZ) and postherpetic neuralgia (PHN) cause significant morbidity in older adults. The incidence and severity of HZ and PHN increase with age in association with an age-related decline in varicella-zoster virus (VZV)-specific cell-mediated immunity (VZV-CMI). VZV vaccines can boost VZV-CMI. Therefore, we tested the hypothesis that VZV vaccination would protect older adu...
متن کاملTreating Herpes Zoster and Postherpetic Neuralgia
Michael C. Rowbotham, MD California Pacific Medical Center Research Institute Department of Anesthesia, UCSF School of Medicine San Francisco, Calif., USA Email: [email protected] P ostherpetic neuralgia (PHN) is t e most frequent chronic complication of herpes zoster ( hingles). Herpes zoster (HZ) represents a reactivation of the varicella zo ter vi us (VZV), a ubiquitous, highly neurotropic,...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 2015
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jiv244